Kind

Mechanisms

Biological processes proposed to drive CLAD.

• Mechanism

  Airway epithelial dysfunction

  Status: proposedEvidence: proposed framework, abstract only

  Dysfunction of the airway lining (epithelium) is named in the review abstract among the pathways involved in CLAD. Proposed framework, abstract only.

• Mechanism

  Aspiration

  Status: proposedEvidence: proposed framework, abstract only

  Aspiration is named in the review abstract among the pathways involved in CLAD. Proposed framework, abstract only.

• Mechanism

  Cytotoxic and senescent T cells

  Status: proposedEvidence: proposed framework, abstract only

  Cytotoxic T cells and senescent T cells are named in the review abstract among the pathways involved in CLAD. Proposed framework, abstract only.

• Mechanism

  Humoral (antibody-mediated) alloimmunity

  Status: proposedEvidence: proposed framework, abstract only

  Humoral, meaning antibody-mediated, immunity is named in the review abstract among the pathways involved in CLAD. Proposed framework, abstract only.

• Mechanism

  Innate immune activation

  Status: proposedEvidence: proposed framework, abstract only

  Innate immune activation is named in the review abstract among the pathways involved in CLAD. Proposed framework, abstract only.

• Mechanism

  Microbial dysbiosis

  Status: proposedEvidence: proposed framework, abstract only

  Dysbiosis, an unhealthy balance of microbes, is named in the review abstract among the pathways involved in CLAD. Proposed framework, abstract only.