Autoantibodies
Evidence level: review-abstract-only; unverified
Named in the review abstract as a candidate biomarker (antibodies directed against the body's own tissue). Unverified beyond the abstract.
As of . Primary source: Burman et al. 2026, J Heart Lung Transplant (DOI; abstract only was read).
Summary
The abstract of the review by Burman and colleagues names this candidate biomarker (antibodies directed against the body's own tissue). The abstract states that the biomarkers named may aid risk stratification, patient enrichment and endotype-guided trials. No performance data are stated, and this record is a stub that is unverified beyond the abstract. Only the abstract of the source review was read; the full text was not read.
Sources and links
Related
Links from this record
- named in (abstract only): CLAD: translating basic science to clinical practice
- candidate for endotype-guided use: Molecular endotypes of CLAD (proposed framework)
Linked from (derived)
- related to: HLA donor-specific antibody and non-HLA antibody testing
- supports: Antibodies to K-α 1 Tubulin and Collagen V Are Associated With Chronic Rejection After Lung Transplantation
- related to: Local intragraft humoral immune responses in chronic lung allograft dysfunction.
- related to: Circulating exosomes with lung self-antigens as a biomarker for chronic lung allograft dysfunction: A retrospective analysis
- related to: De Novo DQ Donor-Specific Antibodies Are Associated with Chronic Lung Allograft Dysfunction after Lung Transplantation
- discusses: Novel biomarkers of chronic lung allograft dysfunction: is there anything reliable?
- related to: Humoral immunity to lung antigens early post-transplant confers risk for chronic lung allograft dysfunction.
- supports: Chronic lung allograft dysfunction is associated with an increased number of non-HLA antibodies
- affects: CLAD is recognised late and no biomarker is validated for early warning
Known gaps in this record
- full text of the source review not read, so the evidence, citations and level of agreement for this item are missing
- funding and conflicts of interest of the source review not read
- assay, performance and validation status not recorded
Information resource only. Not medical advice. Not a substitute for the care of the patient's transplant team.