Mixed phenotype
A CLAD phenotype with obstructive findings, restrictive findings and computed tomography findings together.
As of . Primary source: Verleden et al. 2019 (DOI).
Summary
In the phenotype table of an open-access review of the 2019 ISHLT scheme, the mixed phenotype has all three groups of findings: obstruction, restriction and computed tomography abnormalities. A 2026 open-access study, ScanCLAD, describes mixed as combined obstructive and restrictive features with opacities.
Sources and links
Related
Links from this record
- defined in: Chronic lung allograft dysfunction: Definition, diagnostic criteria, and approaches to treatment: A consensus report from the Pulmonary Council of the ISHLT
- summarised in: Chronic lung allograft dysfunction post-lung transplantation: The era of bronchiolitis obliterans syndrome and restrictive allograft syndrome
- used in: Phenotyping of chronic lung allograft dysfunction in the ScanCLAD study
Linked from (derived)
- compares: Ventilatory capacity in CLAD is driven by dysfunctional airway structure
- compares: Risk assessment of chronic lung allograft dysfunction phenotypes: Validation and proposed refinement of the 2019 International Society for Heart and Lung Transplantation classification system
- compares: Pulmonary epithelial markers in phenotypes of chronic lung allograft dysfunction
- discusses: Phenotyping of chronic lung allograft dysfunction in the ScanCLAD study
- defines: Chronic lung allograft dysfunction: Definition, diagnostic criteria, and approaches to treatment: A consensus report from the Pulmonary Council of the ISHLT
- describes: Chronic lung allograft dysfunction post-lung transplantation: The era of bronchiolitis obliterans syndrome and restrictive allograft syndrome
- affects: Clinical CLAD phenotypes are hard to assign reproducibly
Known gaps in this record
- quotation of the consensus wording (full text not opened)
Information resource only. Not medical advice. Not a substitute for the care of the patient's transplant team.