Kind

Datasets

Public datasets with accession, assay and sample size.

• Dataset

  GEO GSE125478: molecular assessment of rejection and injury in lung transplant biopsies

  Microarray data from 242 single-piece transbronchial biopsies used to identify molecular disease states.

• Dataset

  GEO GSE193150: transcripts in transbronchial biopsies (INTERLUNG)

  Microarray gene expression from 949 transbronchial biopsies of lung transplants, 90 diagnosed as CLAD.

• Dataset

  GEO GSE224210: single-cell and spatial transcriptomics of CLAD and donor control lung

  Single-cell and spatial transcriptomic profiles of whole CLAD and donor control lung tissue.

• Dataset

  GEO GSE274199: single-cell analysis of acute cellular rejection and fibrogenic shift in lung allografts

  Single-cell RNA and ATAC sequencing of lung allograft biopsies from 8 paediatric and young adult patients with and without acute cellular rejection.

• Dataset

  GEO GSE284081: single-nucleus RNA-seq of the fibrotic front in restrictive allograft syndrome

  Single-nucleus RNA sequencing of peripheral lung tissue from 15 RAS patients at retransplantation and 9 control lungs.

• Dataset

  GEO GSE289881: single-cell RNA-seq of fibroblast activation protein in human CLAD

  Single-cell RNA sequencing of lung tissue from CLAD patients and donors, reported in work on FAP as an early CLAD biomarker.

• Dataset

  GEO GSE290834: single-cell RNA-seq of explanted human lungs with CLAD-BOS and cGVHD-BOS

  Single-cell RNA sequencing of explanted lungs from 4 CLAD-BOS patients, 3 chronic GVHD-BOS patients and 3 deceased controls.

• Dataset

  GEO GSE303535: transcripts defining an NK cell-enriched rejection-like state in transbronchial biopsies

  Microarray data from 896 transbronchial biopsies in the INTERLUNG study used to define an NK cell-enriched rejection-like molecular state.

• Dataset

  GEO GSE325801: single-cell profiling of human lung tissue for the periostin RAS study

  Single-cell RNA sequencing libraries from human lung tissue, linked to the JCI Insight periostin paper.

• Dataset

  GEO GSE326968: spatial transcriptomics of IRF7-dependent pathway in CLAD

  NanoString GeoMx whole-transcriptome spatial profiling of human CLAD, non-CLAD transplant and non-transplanted donor lungs.

• Dataset

  GEO GSE94557: whole blood gene expression in lung recipients with CLAD

  Whole blood microarray data from 80 patients (40 stable, 40 BOS) used to seek early blood biomarkers of BOS.