Technical Development of Xe MRI
Evidence level: registry entry; no results posted
A registered phase 1/2 technical-development study of hyperpolarised xenon-129 MRI in children and adults, including lung transplant recipients, sponsored by Cincinnati Children's Hospital Medical Center.
As of . Primary source: ClinicalTrials.gov NCT07823010.
Summary
The ClinicalTrials.gov entry describes a single-group study with an estimated 550 participants that aims to develop and optimise proton and xenon gas MRI techniques for regional cardiopulmonary structure and function: ventilation imaging, alveolar microstructure through the apparent diffusion coefficient, and dissolved-phase xenon. The conditions listed are HSCT and lung transplant recipient. Chronic lung allograft dysfunction is not named as a condition. The registry lists the primary outcome as the xenon gas defect distribution index. No results are posted.
Details
- registry
- ClinicalTrials.gov
- registryId
- NCT07823010
- registryTitle
- Technical Development of Xe MRI in Children and Adults
- sponsor
- Children's Hospital Medical Center, Cincinnati
- registryStatus
- enrolling by invitation
- phase
- Phase 1 / Phase 2
- studyType
- interventional
- enrolment
- 550 (estimated)
- startDate
- 2024-01-01 (actual)
- primaryCompletionDate
- 2029-01 (estimated)
- intervention
- Hyperpolarized 129 Xenon (drug)
- condition
- HSCT; Lung Transplant Recipient
- registryLastUpdatePosted
- 2026-09-16
- registryRead
- 2026-10-10
Sources and links
Related
Linked from (derived)
- registry entry: Hyperpolarised xenon-129 MRI
Known gaps in this record
- acronym: not shown in the registry entry
- results: none posted in the registry
- participating centres and investigators: not recorded
- link to a CLADsolve centre record: not made
Information resource only. Not medical advice. Not a substitute for the care of the patient's transplant team.