Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74) PET/CT Imaging
Evidence level: registry entry; no results posted
A registered phase 3 imaging study of the tracer 18F-FAPI-74 PET/CT in people with heart or lung disease that may cause fibrosis, including lung allograft recipients, sponsored by NHLBI.
As of . Primary source: ClinicalTrials.gov NCT07613099.
Summary
The ClinicalTrials.gov entry describes a non-randomised study with an estimated 210 participants, aged 18 years and older, that compares 18F-FAPI-74 PET/CT with standard-of-care imaging for detecting fibrosis. The conditions listed include lung allograft transplantation, interstitial lung disease, acute lung injury, pulmonary arterial hypertension, cardiovascular diseases and allogeneic stem cell transplantation. Chronic lung allograft dysfunction is not named as a condition. No results are posted.
Details
- registry
- ClinicalTrials.gov
- registryId
- NCT07613099
- registryTitle
- Evaluation of Fibrotic Disease Activity in Cardiopulmonary Disorders Using 18F-Fibroblast Activation Protein Inhibitor (18F-FAPI-74 PET/CT Imaging)
- sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
- registryStatus
- recruiting
- phase
- Phase 3
- studyType
- interventional
- enrolment
- 210 (estimated)
- startDate
- 2026-09-18 (actual)
- primaryCompletionDate
- 2031-05-26 (estimated)
- intervention
- [18F]FAPI-74 (drug); 18F-FAPI-74 PET/CT Imaging (diagnostic test)
- condition
- Allogeneic Stem Cell Transplantation; Lung Allograft Transplantation; Interstitial Lung Disease; Acute Lung Injury; Pulmonary Arterial Hypertension; Cardiovascular Diseases
- registryLastUpdatePosted
- 2026-10-06
- registryRead
- 2026-10-10
Sources and links
Known gaps in this record
- acronym: not shown in the registry entry
- results: none posted in the registry
- participating centres and investigators: not recorded
- link to a CLADsolve centre record: not made
Information resource only. Not medical advice. Not a substitute for the care of the patient's transplant team.