Plasma and Radiologic Biomarkers of Response to ECP in Lung Transplant Recipients With CLAD
Evidence level: registry entry; no results posted
A registered observational study of plasma and MRI biomarkers of response to extracorporeal photopheresis (ECP) in lung transplant recipients with CLAD, sponsored by Brian Keller.
As of . Primary source: ClinicalTrials.gov NCT07434869.
Summary
The ClinicalTrials.gov entry describes an observational study with an estimated 25 participants who have CLAD and are receiving ECP. Blood samples are taken at three points during ECP, and some participants have two lung MRI scans. The registry states that it is not a study of a new drug or treatment and that participants receive the ECP their doctor already recommended. The listed primary outcomes are the change in donor-derived cell-free DNA and the change in a lung microvascular MRI measurement. No interventions are listed in the structured fields. No results are posted.
Details
- registry
- ClinicalTrials.gov
- registryId
- NCT07434869
- registryTitle
- Plasma and Radiologic Biomarkers of Response to ECP in Lung Transplant Recipients With CLAD
- sponsor
- Brian Keller
- registryStatus
- recruiting
- studyType
- observational
- enrolment
- 25 (estimated)
- startDate
- 2026-03-25 (actual)
- primaryCompletionDate
- 2030-02-28 (estimated)
- condition
- Lung Transplant Failure and Rejection; CLAD, Bronchiolitis Obliterans; Extracorporeal Photopheresis
- registryLastUpdatePosted
- 2026-07-14
- registryRead
- 2026-10-10
Sources and links
Related
Links from this record
- studies biomarkers of response to: Extracorporeal photopheresis (ECP)
- Donor-derived cell-free DNA
Linked from (derived)
Known gaps in this record
- acronym: not shown in the registry entry
- phase (not listed for observational studies): not shown in the registry entry
- intervention (none listed in the structured fields): not shown in the registry entry
- results: none posted in the registry
- participating centres and investigators: not recorded
- link to a CLADsolve centre record: not made
Information resource only. Not medical advice. Not a substitute for the care of the patient's transplant team.